Negative Pressure Wound Therapy (NPWT)

Historical Milestones

Usopov and Yepifanov:

Study component in a rabbit surgical wound model used NPWT and a passive drainage control group.
In rabbit models, negative pressures of -75 to -80mmHg increased drainage with minimal or no hemorrhage.
Study component in humans with various wounds evaluated 1,616 subjects.
Sterile wounds were treated with continuous NPWT at -70 to -80mmHg for 2-3 days.
Purulent wounds were treated with debridement and irrigation and continuous NPWT at -30mmHg to -40mmHg for 6-8 days.
Pressures not over -80mmHg in both study components provided active drainage without the likelihood of hemorrhage.

 

 

 

 

 

 

NPWT
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Wound Healing 101
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